Confirming Variants in Next-Generation Sequencing Panel Testing by Sanger Sequencing
نویسندگان
چکیده
منابع مشابه
Systematic Evaluation of Sanger Validation of Next-Generation Sequencing Variants.
BACKGROUND Next-generation sequencing (NGS) data are used for both clinical care and clinical research. DNA sequence variants identified using NGS are often returned to patients/participants as part of clinical or research protocols. The current standard of care is to validate NGS variants using Sanger sequencing, which is costly and time-consuming. METHODS We performed a large-scale, systema...
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ژورنال
عنوان ژورنال: The Journal of Molecular Diagnostics
سال: 2015
ISSN: 1525-1578
DOI: 10.1016/j.jmoldx.2015.03.004